Home
Resource
Taste and endocrine factors in women with gestational diabetes mellitus
PDF
PDF format is widely accepted and good for printing.
Plug-in required
PDF-1(707.25 kb)
Citation & Export
View Usage Statistics
Staff View

Citation & Export
Hide

Simple citation

Belzer, Lisa Michelle. Taste and endocrine factors in women with gestational diabetes mellitus. Retrieved from https://doi.org/doi:10.7282/T32R3S2V

Export

Click here for information about Citation Management Tools at Rutgers.

Statistics
Hide

Description

Uniform TitleTaste and endocrine factors in women with gestational diabetes mellitus
NameBelzer, Lisa Michelle (author); Tepper, Beverly (chair); Watford, Malcolm (internal member); Shapses, Susan (internal member); Smulian, John (outside member); Rutgers University; Graduate School - New Brunswick
Date Created2008
Other Date2008-01 (degree)
SubjectNutritional Sciences, Diabetes in pregnancy
Extentxv, 165 pages
DescriptionGestational diabetes mellitus (GDM) is hyperglycemia first identified during pregnancy. Many metabolic parameters increase across normal gestation, but may exceed those levels in pregnancies where GDM develops. Studies on the time course and pattern of metabolic factors in GDM are conflicting. Additionally, past research suggests changes in cravings and dietary intake during normal pregnancy and taste alterations in diabetes and pregnancy. Such parameters have been studied only on a limited basis in women with GDM. In this dissertation, we examined metabolic, taste and dietary measures across pregnancy.
The temporal profile of insulin, cortisol and leptin was determined in women who developed GDM and those who remained normal glucose tolerant (NGT). Fasting insulin levels were higher at 24-28 weeks gestation than during postpartum in women with GDM, however it was not until 34-38 weeks that insulin differed from postpartum in NGT women. Both pregnant groups showed similar increases in cortisol levels across gestation. From 16-20 weeks to 24-28 weeks, leptin rose rapidly in women with GDM and was marginally higher in GDM women relative to NGT women at 24-28 weeks. By 34-38 weeks, leptin values did not differ between pregnant groups.
We also studied pregnancy and GDM effects on sweet taste perception and preference, and examined relationships of taste parameters with circulating hormones. Women with GDM exhibited higher preference for sucrose-sweetened milk as well as positive relationships between liking of glucose solutions and sucrose-sweetened milk and insulin and leptin, respectively. Women with NGT reported higher intake of all sweet food and beverage at 24-28 weeks, primarily as fruit and fruit juice, while women with GDM reported higher frequency of sweet cravings at 34-38 weeks gestation.
These results suggest that women challenged with concurrent pregnancy and diabetes exhibit early rises in insulin and leptin during gestation and such endocrine changes may be related to elements of sweet taste. Additionally, during late gestation, although women with GDM report following a carbohydrate controlled diet, they show a higher preference and craving for sweet taste. In GDM, alterations in sweet taste and differences in sweet cravings and food intake may be metabolically or psychologically based.
NotePh.D.
NoteIncludes bibliographical references.
Genretheses, ETD doctoral
Persistent URLhttps://doi.org/doi:10.7282/T32R3S2V
LanguageEnglish
CollectionGraduate School - New Brunswick Electronic Theses and Dissertations
Organization NameRutgers, The State University of New Jersey
RightsThe author owns the copyright to this work.
Version 8.5.5
Rutgers University Libraries - Copyright ©2024