DescriptionIn this thesis, we evaluate different Open Source Content Management Systems (CMSs) and determine their appropriateness for scientific research laboratories' website content management. We describe different CMSs and evaluate them based on the following criteria: ease of installation, usability, maintenance and updates, scalability, community strength and support, user roles and workflow, security, and Web 2.0 features. We then choose one of these systems, Drupal, and demonstrate its effectiveness for two different scientific websites, Bio-1 and Vizlab. Drupal allows integrating new features using community contributed modules and easy future up-gradation. Successful implementation of both projects using Drupal highlights the importance of Open Source CMSs.